Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 15 - Jul 20
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
CGRP Recombinant Rabbit mAb (S-2490-74)Product Specification Host Rabbit Antigen CGRP Synonyms Calcitonin gene related peptide 1; CGRP1; Alpha type CGRP; Calcitonin gene related peptide I (CGRP I); CALC1; CALCA Immunogen Synthetic Peptide Location Secreted Accession P06881 Clone Number S 2490 74 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Hu, Ms, Rt Positive Sample TT Purification Protein A Concentration 2 mg ml Conjugation Unconjugated Physical Appearance
Product Specification
| Host | Rabbit |
| Antigen | CGRP |
| Synonyms | Calcitonin gene-related peptide 1; CGRP1; Alpha-type CGRP; Calcitonin gene-related peptide I (CGRP-I); CALC1; CALCA |
| Immunogen | Synthetic Peptide |
| Location | Secreted |
| Accession | P06881 |
| Clone Number | S-2490-74 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P |
| Reactivity | Hu, Ms, Rt |
| Positive Sample | TT |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000-1:10000 | Hu |
| IHC-P | 1:500 | Hu, Ms, Rt |
Background
CGRP (calcitonin gene-related peptide) is a 37-amino-acid neuropeptide produced by tissue-specific splicing of the CALCA gene in primary afferent sensory neurons and central neurons; it signals through a heterodimeric receptor composed of the G-protein-coupled receptor CALCRL and the accessory protein RAMP1, potently dilating cerebral and dermal vasculature, modulating nociceptive transmission, and mediating neuro-inflammatory responses, making it a key target for monoclonal antibodies and small-molecule antagonists in the prevention of migraine and the treatment of cluster headache.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy